Tag: Ischemia

That is, on average, a patient who exercises to angina with three-vessel CAD is likely to have a greater amount of ischemic myocardium than a patient with two-vessel disease who also exercises to angina. Moreover, the same reasoning suggests that a larger sample population of normal subjects may have allowed a statistically significant difference in […]

The ability of BSPM to spatially discriminate the primary artery involved in the ischemic process is not yet established. Eigenfunction analysis has been reported to effectively discriminate left anterior descending from right CAD. In contrast, the data of this study and one other study using isointegral analysis suggest that there is marked overlap of the […]

One other implication of this study concerns the residual ST integral decrease at 5 min postcessation of exercise. Residual ST decrease was also a finding in our previous study of patients with isolated left anterior descending CAD. The findings of this larger study sample provide additional support for the concept that clinical myocardial ischemia is […]

Certainly, the epidemiologic data from two recent studies of large patient populations have shown that the degree of exercise ST deviation, as measured from 12- and 15-lead electrocardiograms is a very strong and independent predictor of future coronary death and other clinical cardiac endpoints. A corollary of this reasoning is that CAD patients who fatigue […]

There were three major findings in this study. First, exercise BSPM provided quantitative discrimination among individual patients and patient groups with single- and multiple-vessel CAD. On average, patients with underlying multiple-vessel CAD and angina-limited exercise had significantly greater exercise ST integral decrease than patients with single-vessel CAD and angina. The CAD patients who fatigued during […]

Quantitative Coronary Angiography The modified Gensini scores of all CAD patients are displayed in Table 1. Groups 2 and 3 had similar mean scores (68 ± 30, group 2 vs 56 ± 18, group 3; NS); both were significantly (p<0.05) higher than those of group 4 and group 2 mean scores were also significantly (p<0.05) […]

As a discriminating variable, sum ST decrease  — 4,000mV*s, cessation minus rest, appeared to provide the best criterion for prediction of single-vs multiple-vessel CAD in patients who achieved angina (Table 2). Retrospective application of this criterion to CAD groups 1 to 3 yielded a sensitivity of 85 percent, a specificity of 70 percent, a positive […]

The group mean ST integral maps of the left anterior descending, right and circumflex artery subgroups of CAD patient group 1 (Table 1) are illustrated in Figure 5. There were major differences in resting ST patterns between the left anterior descending patients maps and those of the other 2 subgroups (Fig 5). There was, however, […]

The group mean ST isointegral maps of the four CAD groups and the control subjects are illustrated in Figure 4. As can be seen, the spatial changes in ST patterns from rest to peak exercise were similar in all four patient groups, namely the development of absolute negative ST integral values over the left lateral […]

BSPM The exercise tolerance test data of the 51 CAD patients are presented in Table 2 and that of the normal control subjects in Table 3. The average peak exercise heart rates were not different among the five study groups and averaged, overall, 99 beats/min (Tables 2 and 3).