Respiratory Failure of Acute Organophosphate and Carbamate Poisoning: Results (2)Table 2 summarizes the number of patients by different degree of severity and their relationship with RF. The patients with RF had more severe poisoning. Buy Asthma Inhalers Online
Cardiovascular collapse occurred on arrival in 19 patients (17.8 percent); 17 developed acute RF, and two developed subacute RF. Pneumonia developed in 28 patients (26.2 percent); 19 had acute onset during the first 24 hours after poisoning, and nine had subacute onset between 4 and 96 hours after poisoning. The relationship between pneumonia and RF is summarized in Table 3. Most patients with pneumonia developed RF.
Signs and symptoms were not completely recorded in all cases in this retrospective study. Table 4 illustrates only the positive numbers and their distribution in different degrees of severity. Although there was no correlation between severity and incidence of signs and symptoms, the patients with higher severity had significantly higher mortality (Table 4). There were 14 kinds of organophosphate compound contributing to the poisoning in our patients; merinphos and parathion were the most common. No special organophosphate compound resulted in RF or fatal outcome more frequently than others.

Table 2—Relationship between Respiratory Failure and Severity in Acute Organophosphate and Carbamate Poisoning

Total (%) Severe (%) Moderate (%) Mild (%) Very Mild (%)
Acute RF .35 (.33) 28 (80) 3 (8) 2 (6) 2 (6)
Subacute RF 8 (7) 7 (88) 1 (12) 0 0
Without RF 64 (60) 14 (22) 10 (16) 16 (25) 24 (37)
Total 107 49 (46) 14 (13) 18 (17) 26 (24)

Table 3-—Relationship between Respiratory Failure and Pneumonia in Acute Organophosphate and Carbamate Poisoning

Total (%) Acute P (%) Subacute P (%) Without P (%)
Acute RF 35 (33) 15 (43) 3 (9) 17 (48)
Subacute RF 8 (7) 2 (25) 5 (63) 1 (12)
Without RF 64 (60) 2 (3) 1 (2) 61 (95)
Total 107 19 (18) 9 (8) 79 (74)

Table 4—Distribution of Positive Clinical Signs, Symptoms, and Outcome by Severity in Acute Organophosphate and Carbamate Poisoning

Total Sev (%) Mod (%) Mild (%) V Mild (%)
Total 107 49 (46) 14 (13) 18 (17) 26 (24)
Sweating 21 6 (29) 6 (29) 3 (14) 6 (28)
Salivation 42 22 (52) 6 (14) 5 (12) 9 (22)
Nausea 47 19 (41) 7 (15) 10 (21) 11 (23)
Miosis 83 43 (52) 10 (12) 15 (18) 15 (18)
Disturbed consciousness 54 28 (52) 6 (11) 9 (17) 11 (20)
Apnea 16 11 (69) 2 (13) 2 (13) 1 (7)
Cardiovascular collapse 19 14 (74) 2 (11) 2 (11) 1 (6)
Outcome
Alive 85 31 (37) 11 (13) 18 (21) 25 (29)
Died 22 18 (82) 3 (14) 0 (0) 1 (4)