Quality of Life in Patients with Obstructive Sleep Apnea
Obstructive sleep apnea (OSA) is characterized by recurrent obstruction of the upper airway, which results in episodic asphyxia, oxygen desaturations, and disruption of the normal sleep pattern. The majority of OSA patients have symptoms related to poor quality sleep, such as excessive daytime sleepiness and tiredness, lack of concentration, memory impairment, and at times psychological disturbances. OSA is also associated with cardiovascular and cerebrovascular morbidity and mortality. As a result of these symptoms and functional impairments, OSA patients often report having a poor quality of life in social, emotional, and physical domains.
Treatments for OSA include positional training, weight loss, avoidance of alcohol and sedative drugs, mandibular advancement devices, nasal continuous positive airway pressure (nCPAP), and upper airway surgery Here buy tavist online. The most commonly used and most effective treatment modality has been nCPAP. nCPAP has been shown to decrease the frequency of apneic events and oxygen desaturation during sleep, and to reduce the severity of sleep disturbances and daytime sleepiness.
In a cross-sectional study by Tousignant et al, nCPAP therapy increased quality adjusted life years, We undertook the present prospective longitudinal study to determine the impact of OSA and nCPAP therapy on the overall quality of life, In previous studies, both disease-specific and general assessment tools were used for the estimation of the quality of life measures in OSA. In this study, however, we were interested in evaluating the overall quality of life, rather than symptoms directly associated with the disease.
Materials and Methods
Twenty-nine patients who were referred to the sleep laboratory for evaluation of sleep-disordered breathing were prospectively enrolled in the study. Those patients with conditions diagnosed as OSA (apnea/hypopnea index > 15/h) and given nCPAP therapy were included in this study. Patients who had other sleep disorders or received treatment other than nCPAP for their OSA were not included in this study.