Subjects
The patient group consisted of 51 unselected adults with CAD referred to the Cardiac Investigation Service of the Victoria General Hospital (Table 1 and 2). The inclusion criteria were a clinical history of exercise-associated visceral chest pain compatible with angina, willingness to perform an exercise test according to the study protocol and angiographically demonstrated CAD. Excluded were patients with bundle branch block, artificial pacemakers or any physical disability that precluded exercise tolerance testing. All study subjects had coronary arteriography within 24 h of exercise testing. Buy Asthma Inhalers Online
Based on their exercise test endpoints and coronary angiographic anatomy and blinded from all other study data, the CAD patients were divided into four groups.
Ail CAD patients in groups 1 to 3 reached an exercise endpoint of clinical ischemia (angina, n = 35, ST depression in lead Vs, n = 1) (Table 2). Group 1 was composed of 23 subjects with critical (^70 percent luminal narrowing) stenosis isolated to a single coronary artery (Table 1). Fourteen group 1 patients had isolated left anterior descending CAD; four patients had isolated right CAD; and five patients had isolated circumflex CAD (lable 1). Group 2 was composed of eight patients with critical two-vessel CAD (Table 1). Group 3 was composed of five patients with critical three-vessel CAD (lable 1).

Table 1—Clinical, Angiographic and Besting Body Surface Map Data of 51 Study Subjects with Coronary Artery Disease

Patient

Age (yr), Sex

LV Wall Motion Abnormality

Percent Luminal Narrowing

Gensini

Score

2 Negative ST (mV-s)

LAD

RCA

CX

Group 1

1

73, M

0

99

0

0

42

-1,540

2

32, M

+

75

0

0

10

– 870

3

78, F

+

90

0

0

20

– 520

4

41,F

+

99

0

0

24

– 617

5

60,M

+

100

0

0

76

-2,698

6

54,M

0

100

0

0

89

-1,703

7

61,F

+

99

0

0

40

-1,341

8

47,F

0

90

0

0

13

-1,943

9

36,M

+

99

0

0

40

-1,065

10

60,M

0

99

0

0

24

-1,077

11

55, M

0

99

0

0

24

– 955

12

57, M

+

90

0

0

17

– 959

13

62, M

+

99

0

0

26

– 596

14

59,M

+

100

0

0

36

-1,901

15

58, M

+

0

100

0

45

-4,279

16

35,M

0

0

99

0

14

-1,781

17

54,F

+

0

100

0

28

-3,324

18

54,M

+

0

99

0

17

-1,835

19

41,M

0

0

0

100

28

-1,163

20

32, F

0

0

0

90

8

-1,599

21

63,F

0

0

0

99

16

-2,818

22

63,M

+

0

0

75

6

– 465

23

36,M

0

0

0

99

42

-1,321

Mean±SD

53

30

-1,581

13

20

949

Group 2

24

59, M

0

100

90

0

90

-1,622

25

64,F

+

99

100

0

67

-1,500

26

36,M

+

90

75

0

29

-2,595

27

58,M

+

90

0

80

40

-2,948

28

56,M

+

90

0

100

50

-1,468

29

67,F

0

70

0

100

104

-1,244

30

64, M

+

100

0

99

56

-1,009

31

44,M

+

100

0

100

109

– 326

Mean±SD

56

68

-1,589

11

30

839

Group 3

32

59,M

+

100

100

75

58

– 902

33

53,M

+

75

100

90

52

-2,356

34

48,M

0

75

90

75

27

-1,431

35

45,M

+

75

100

100

74

– 949

36

60,F

+

99

99

99

67

-1,097

Mean ± SD

53

56

-1,347

7

18

601

Group 4

37

44,M

+

100

0

0

31

– 510

38

62,F

+

0

100

0

16

-2,760

39

62, F

+

75

0

0

10

– 983

40

45,M

+

99

50

90

64

-1,734

41

70,M

0

40

40

0

1

– 813

42

60,F

0

90

0

0

20

-1,064

43

47, M

0

0

75

75

14

-1,660

44

54,M

0

90

0

0

24

-1,635

45

44,M

0

0

90

100

36

-1,211

46

63,M

+

70

0

70

14

-1,868

47

51,M

0

0

60

90

12

-1,748

48

48,M

0

75

0

0

6

-1,357

49

37, M

0

95

0

0

40

-1,519

50

48,M

+

60

0

0

8

-1,097

51

55,M

+

90

100

0

50

-1,326

Mean ± SD

53

23

-1,419

9

18

534

Table 2—Exercise Test Data of 51 Study Subjects with CAD 

Thallium

1 ST Decrease (^jlV-s)

Clinical

Peak

Reversible

Cessation

Recovery 5

Patient

Endpoint

Heart Rate

Defect

Score

-Rest

-Rest

Group 1

1

CP

101

+

10

– 3,784

– 1,695

2

98

+

6

– 3,616

– 469

3

94

+

10

– 727

– 514

4

112

0

0

– 2,511

-3,499

5

ECG

98

+

13

– 9,043

-6,202

6

CP

101

+

10

– 4,290

-2,707

7

116

+

1

– 7,235

-5,440

8

105

+

8

– 4,114

-3,112

9

114

+

1

– 3,308

– 1,291

10

75

+

2

– 6,394

-4.818

11

81

+

8

– 1.297

-1,049

12

88

+

2

– 1,682

– 968

13

111

0

0

– 2,902

-1,833

14

79

+ ‘

10

– 2,683

-2,486

15

81

0

0

– 5,252

– 869

16

96

+

6

– 2,581

– 1,241

17

98

+

11

– 3,776

-2.163

18

109

+

6

– 3.065

-2,746

19

96

+

3

– 1,590

– 422

20

129

+

1

– 3,351

-1,648

21

85

+

2

– 2,935

-2,498

22

99

0

0

– 731

-1,292

23

90

+

3

– 2,418

– .352

Mean±SD

98

5

– 3,447

— 2,144

13

4

2,011

1,607

Group 2

24

103

0

0

– 9,893

-5,044

25

92

+

13

– 6,537

-3,423

26

104

0

0

– 5,190

-2,590

27

104

0

0

– 2,996

-2,039

28

110

0

0

– 4,705

– 712

29

84

0

0

– 2,715

-3,943

30

120

+

9

– 6,207

-3,246

31

91

+

8

– 7,35span class=”font2″5

-1,537

Mean ± SD

101

4

– 5,700

-2,817

12

5

2,.353

1,389

Group 3

32

93

+

9

– 8,386

-2,196

33

98

+

8

– 7,364

-4,548

34

92

0

0

– 5,159

-2,264

35

108

+

12

-11,214

-3,478

36

77

+

6

– 4,288

-2,332

Mean ± SD

94

7

– 7,282

– 2,964

11

4

2,746

1,031

Group 4

37

Fatigue

89

+

3

– 1,928

1,737

38

102

+

1

– 2,917

3,232

39

80

0

0

– 3,939

-1,649

40

92

0

0

– 3,117

-1.685

41

81

+

6

– 598

-2,1.58

42

103

0

0

– 4,050

-4,282

43

93

+

2

– 4,928

-2,912

44

103

0

0

– 3,009

-3,299

45

116

+

2

– 2,851

-1,946

46

96

+

6

– 4,575

-5,327

47

102

+

2

– 5,371

-2,402

48

85

+

3

– 2,823

-1,617

49

88

0

0

– 1,215

– 76

50

158

0

0

– 2,138

-1,905

51

100

+

6

– 3,814

– 599

Mean ± SD

100

2

– 3,152

-2,322

19

2

1,337

1,338