The other measures of diaphragmatic activity also demonstrated greater reduction during PPV. Figure 3 and Table 1 illustrate the reduction in the PTI, peak Pdi, and CV-Vt. The reduction of PTI during NPV was different from QB (58 percent, p = 0.05) and the reduction during PPV was different from both QB (29 percent, p = 0.01) and NPV (p = 0.05). The peak Pdi was similarly reduced during PPV to 47 percent of baseline (p = 0.01). The CV-Vt during PPV was significantly lower (3 percent) when compared to NPV (CV-Vt=13 percent) and QB (CV-Vt =18 percent) (p = 0.01).
Figure 4 shows the relationship between the change in etC02 and iEMG during both PPV and NPV Both combined (PPV + NPV) and separate analysis failed to show a significant relationship between the two variables (r=0.210, p = 0.349). birth control pills
The relationship between iEMG and peak Pdi and PTI was examined. During QB, there was a significant relationship between iEMG and both indices (r = 0.818 and r = 0.801, respectively, p<0.01). There was also a significant relationship between the change in iEMG and change in PTI during NPV and PPV (y = 0.90x- 23.04; r = 0.88, p<0.01) (Fig 5).
Table 1—Means of Breath-by-Breath Sampling during Last Three Minutes of Each Study Session Expressed as Mean ± SD
|Ve,* L/min||Peak Pdi,t cm H20||ETCOa,t %|
|Normals (n = 5)|
|QB||7.3± 1.3||16.8 ±5.2||5.8 ±0.5|
|COPD (n = 6)|
Figure 4. Scattergram compares the change in iEMG and the change in etC02 for all subjects. No significant relationship was found. Symbols as defined in Figures 2 and 3.
Figure 5. Significant relationship between the change in iEMG and the change in PTI (p<0.01) for all subjects. Symbols as defined in Figures 2 and 3.
Category: Lung function
Tags: neuromuscular, neuromuscular disease, patients copd, ventilatory muscle