Diagnostic, Morphologic, and Histopathologic Correlates in Bronchogenic Carcinoma (7)
Cytologic specimens were classified as “positive” only when the cellular morphology contained frankly malignant characteristics; for this report, all other interpretations, including marked atypia, were pooled together as “negative” data.
The statistical significance of dissimilar frequencies was tested using the x2 method. A value of p<0.01 was considered significant. ampicillin antibiotic
The study population (1,045 patients who underwent bronchoscopy and ultimately were proven to have lung cancer) had the following anthropometric characteristics: median age, 63 years; range, 34 to 87 years; and M/F sex ratio, 8/1 (930 male patients and 115 female patients). In all, 782 pathologic diagnoses were available.
Figure 2 shows the overall diagnostic accuracy of the diverse techniques of sampling: forceps biopsies were positive in 79 percent of the 841 performed biopsies (64 percent of the entire sample); brushings were positive in 38 percent of372 biopsies (14 percent of all patients); and washings were positive in 32 percent of 1,009 biopsies (31 percent of 1,045). More than one positive finding occurred in 309 bronchoscopies out of 1,045 (30 percent).
Figure 2. Overall diagnostic yield of three bronchoscopic routine techniques. FB, Forcep biopsies; BB, brush biopsies; and BW, bronchial washings.