Diagnostic, Morphologic, and Histopathologic Correlates in Bronchogenic Carcinoma (7)Cytologic specimens were classified as “positive” only when the cellular morphology contained frankly malignant characteristics; for this report, all other interpretations, including marked atypia, were pooled together as “negative” data.
The statistical significance of dissimilar frequencies was tested using the x2 method. A value of p<0.01 was considered significant. ampicillin antibiotic

Results
The study population (1,045 patients who underwent bronchoscopy and ultimately were proven to have lung cancer) had the following anthropometric characteristics: median age, 63 years; range, 34 to 87 years; and M/F sex ratio, 8/1 (930 male patients and 115 female patients). In all, 782 pathologic diagnoses were available.
Figure 2 shows the overall diagnostic accuracy of the diverse techniques of sampling: forceps biopsies were positive in 79 percent of the 841 performed biopsies (64 percent of the entire sample); brushings were positive in 38 percent of372 biopsies (14 percent of all patients); and washings were positive in 32 percent of 1,009 biopsies (31 percent of 1,045). More than one positive finding occurred in 309 bronchoscopies out of 1,045 (30 percent).

Figure-2

Figure 2. Overall diagnostic yield of three bronchoscopic routine techniques. FB, Forcep biopsies; BB, brush biopsies; and BW, bronchial washings.