Obstructive Sleep Apnea

The improvement in these domains was independent of the baseline apnea/hypopnea index or other indicators of OSA severity. The degree of impairment in quality of life domains but not the severity of disease determined the degree of improvement with nCPAP. In a study by Engleman et al of 204 nCPAP users, there was a significant […]

None of these variables had any significant bearing on the changes in SF-36 parameters with nCPAP treatment. However, significant correlations were found between quality of life scores on the SF-36 at baseline and prior to nCPAP administration and the subsequent change in scores after treatment, except for “role physical.” In other words, patients with lower […]

The patients had significantly decreased health status in all domains of SF-36—role functioning, physical functioning, vitality, mental health, and health percep-tions—when compared with age-matched control subjects (Fig 2). To determine the effect of the severity of sleep apnea on the quality of life, the indicators of disease severity, the RDI and arousal indices, and the […]

Apneic variations were classified using the following definitions: apnea was present when there was at least an 80% reduction in airflow for > 10 s, obstructive apnea was present when respiratory efforts were present, central apnea was present when respiratory efforts were absent, and mixed apneas occurred when there was a central component followed by an […]

Study Protocol Prior to the onset of nCPAP therapy and “split-night” polysomnography, each patient completed a previously validated health questionnaire, the Medical Outcomes Study Short Form-36 (SF-36), and baseline anthropomorphic measurements were recorded. The optimal nCPAP level was determined in the laboratory during the study. Eight weeks later, the SF-36 was readministered, and each patient […]

Obstructive sleep apnea (OSA) is characterized by recurrent obstruction of the upper airway, which results in episodic asphyxia, oxygen desaturations, and disruption of the normal sleep pattern. The majority of OSA patients have symptoms related to poor quality sleep, such as excessive daytime sleepiness and tiredness, lack of concentration, memory impairment, and at times psychological […]

There was an increase in PaC02 from 40 to 43 mm Hg after oxygen administration. However, daytime sleepiness was not improved by oxygen administration. Alford and colleagues demonstrated that nasal oxygen at 4 L/min increased the length of sleep disordered breathing events, as well as arterial Pco2, resulting in a lower pH at the end […]

To our knowledge, this is the first study to compare the effects of nasal CPAP and nasal oxygen treatment on the major sequelae of mild obstructive sleep apnea. The main findings of our study were that oxygen does not reduce the total number of sleep disordered breathing events compared to baseline or placebo, although CPAP […]

As there was only one test form for the Rey Complex Figure, practice effects may have accounted for the differences seen on this measure, particularly for nasal CPAP, as treatment and time of measurement were confounded. While there was a marginal effect of treatment on the measure of constructional praxis (Rey copy; (F[3,21] = 2.82, […]

Selected neuropsychologic variables are reported in Table 6. Given the large number of possible dependent measures that could be analyzed from the different neuropsychologic tests, we chose several measures for analysis, a priori, based on the data reported by Berry et al. These measures included sustained visual attention (Ruff 2 & 7 Test), motor ability […]