Although it is highly unlikely that this course could have been reversed without HFPV, this possibility has not been tested and therefore cannot be excluded. The absence of a control group managed without HFPV does not allow conclusions on outcome differences. This is the reason we elected to report only the short-term ventilatory and hemodynamic […]

Another interesting observation derived from this study is based on the comparison of selected values among patients. It is obvious that the conversion to HFPV rapidly improved the Pa02/Fl02 ratio, increased the MAP, and decreased the PIP as shown by the comparison of the last value recorded before HFPV with the first value after initiation of […]

Although Emerson conceived of high-frequency oscillation in 1952 and Butler et al clinically validated his concept in 1980, the development of HFPV by the VDR is a relatively new and underexplored topic. In the limited published experience with HFPV in neonates, it is suggested that this method may improve oxygenation and CO2 elimination in premature […]

The SICU and MICU patients were evaluated separately for all monitored values. In Table 4, the following two observations were made: (1) SICU patients demonstrated significant improvement in Sa02, pH, PIP, and MAP after switching from CV to HFPV; and (2) MICU patients showed significant improvement in Pa02/Fl02, PIP, and MAP after converting to HFPV. […]

The second way of analyzing the data was to examine the rates of change per hour of each parameter during the 48 h before and the 48 h after starting HFPV for each patient, and compare these values using the paired Student’s t test and a significance level of p < 0.05. The third way […]

Data Collection and Statistical Analysis Values for the following parameters were collected from a computerized ICU database: Pao2/Flo2, partial Paco2, pH, PIP, MAP, Sao2, mean arterial BP (MBP), oxygen delivery index (Do2I), oxygen consumption index (Vo2I), oxygen extraction ratio (O2ER), and intrapulmonary shunt fraction (Qs/Qt). These data were inserted prospectively into the ICU-computer database and collected retrospectively for […]

The piston is driven by a high-pressure gas supply at a high-frequency rate of 200 to 900 beats/min, superimposed on a conventional inspiratory/expiratory pressure-controlled cycle that is set at a rate of 10 to 15 breaths/min. There are five control parameters: (1) peak inspiratory pressure (PIP), (2) inspiratory time (Ti), (3) Te, (4) positive end-expiratory pressure (PEEP) and continuous […]

Materials Patients who developed ARDS and were placed on HFPV from June 1994 to December 1995 were included in this study. ARDS was considered present if (1) the Pao2/fraction of inspired oxygen (Fio2) ratio was < 200, (2) bilateral diffuse lung infiltrates were present on a plain chest radiograph, and (3) wedge pressure was < 18 mm Hg. Patients […]

High-frequency ventilation has emerged during the last 10 years as a way of maintaining gas exchange while, it is hoped, limiting respirator-associated lung parenchymal injury. This mode of ventilation is mainly administered by three types of equipment: (1) jet ventilators, (2) oscillators, and (3) flow interrupters. Although high-frequency jet ventilation has been extensively tested in pediatric […]